Microcrystalline Cellulose (MCC) 200 is a coarse-grade excipient engineered for superior flowability, impressive compressibility, and reliable mechanical strength. Its larger particle size distinguishes it from finer MCC grades, making it ideal for high-speed tablet pressing, direct compression, and granulation processes where consistent powder performance and content uniformity are essential.
MCC 200 is derived from purified plant cellulose that is partially depolymerized. With a significantly larger average particle size (around 200 µm), this grade is specifically optimized to improve bulk flow, reduce die-bridging, and support efficient dosage form production. Thanks to its plastic deformation behavior under compression, MCC 200 forms strong interparticle bonds, yielding durable tablets while also facilitating rapid disintegration through its porous structure. nbinno.com+1
Exceptional Flowability
Larger particles reduce friction and bridging, enabling smooth, consistent feed in tablet presses and capsule filling.
Robust Binder & Diluent
Offers high binding strength and structural support even at low compaction forces.
Effective Disintegration
Hydrophilic and porous, MCC 200 absorbs water and swells, promoting disintegration and uniform API release.
Stable & Inert
Chemically inert and compatible with a broad range of APIs, making it reliable for sensitive formulations.
Flexible Granulation Options
Excellent for both direct compression and roller compaction workflows. answercenter.iff.com
| Parameter | Typical Specification |
|---|---|
| Appearance | White to off-white powder |
| Particle Size | ~200 µm (coarse grade) answercenter.iff.com |
| Bulk Density | Moderate, optimized for flow |
| Moisture Content | 3–5% (typical for MCC 200) |
| pH (10% slurry) | ~5.0–7.5 |
| Loss on Drying | ≤ ~5% |
| Purity | Pharmaceutical or food-grade |
| Functionality | Binder, diluent, disintegrant |
| Packaging | 20–25 kg moisture-resistant bags |
Pharmaceutical Tablets
Direct compression tablets where flow and uniform fill are critical
Dry granulation / roller-compaction formulations
Large or high-speed batch production lines
Capsules
Acts as a high-flow filler for capsule blends
Enhances uniformity in capsule filling
Nutraceuticals & Supplements
Used in bulk dietary supplement tablets
Supports stable, high-dose or low-dose formulation design
Other Industrial Uses
Stabilizer or binder in non-pharma powder blends
Potential use in food-grade applications where high flow is needed
GMP-Certified Production — Manufactured in rigorously controlled environments
Consistent Quality — Stringent quality checks for particle size, moisture, and purity
Technical Support — Expert formulation guidance, including flow optimization and compatibility testing
Global Supply — Reliable inventory and fast shipping to support your production timelines
Custom Options — Tailored grades (particle size, moisture, density) available to match your specific needs
1. How does MCC 200 differ from MCC 101?
MCC 200 has a larger average particle size, which leads to better flow and easier handling, compared to the finer MCC 101.
2. Is MCC 200 suitable for direct compression?
Yes — it’s specifically optimized for direct compression and large-scale tablet production due to its excellent flow and binding characteristics. answercenter.iff.com
3. Will MCC 200 slow down disintegration?
No. Its porous structure and hydrophilic nature actually support rapid water uptake and disintegration. nbinno.com
4. Is MCC 200 compatible with sensitive APIs?
Yes. MCC 200 is chemically inert and does not interact with most active ingredients, preserving API stability. nbinno.com
5. Can you provide a custom grade of MCC 200?
Yes, we offer customized MCC 200 with tailored particle size, moisture content, and other parameters to meet your formulation demands.
If you’re looking for high-flow, pharmaceutical-grade MCC 200 for your tablet or capsule production, partner with Besty Pharma. We deliver reliable, high-quality excipients and expert formulation support to help you scale successfully.
