Microcrystalline Cellulose (MCC) 301 is a specialized coarse-particle excipient developed for applications that require exceptional flowability and mechanical strength. Thanks to its larger particle size, MCC 301 offers superior bulk handling and reduced compression risk, making it an excellent choice for high-speed tableting and large-scale production.
Manufactured in Besty Pharma’s GMP-certified facility, MCC 301 ensures outstanding quality, batch consistency, and adaptability for both pharmaceutical and nutraceutical manufacturers who prioritize efficiency and reliability.
MCC 301 is a large-particle, partially depolymerized plant cellulose derivative designed to optimize flow and compressibility in demanding solid-dosage applications. Its granular structure helps minimize aeration and bridging, improving feed into tablet presses or capsule machines. Under compression, MCC 301 exhibits strong plastic deformation and creates a dense network of interparticle bonds, delivering robust tablet strength without sacrificing batch uniformity.
Exceptional Flow Performance
Coarse-grained structure ensures smooth bulk flow, minimizing bridging and flow interruptions in high-speed equipment.
High Mechanical Strength
Produces tablets with excellent hardness and low friability, suitable for demanding production and transport conditions.
Efficient Direct Compression
Excellent compression behavior without the need for granulation — ideal for fast and cost-effective tablet manufacturing.
Effective Powder Handling
Reduced dust and improved handling during blending, weighing, and compression processes.
Consistent Disintegration
Porous morphology provides rapid water uptake, promoting reliable disintegration and drug release.
High Purity & Compatibility
Inert and chemically stable, MCC 301 is suitable for a wide variety of APIs and formulation types.
| Parameter | Typical Specification |
|---|---|
| Appearance | Off-white to white granular powder |
| Particle Size | Coarse grade (significantly larger than MCC 101/102) |
| Bulk Density | Optimized for flow and compression |
| Moisture Content | ≤ 6% (typical) |
| pH (10% slurry) | ~5.0–7.5 |
| Loss on Drying | ≤ ~7% |
| Solubility | Dispersible but insoluble in water |
| Functional Role | Filler, binder, direct-compression excipient |
| Packaging | 20 kg / 25 kg moisture-barrier kraft bags |
Pharmaceutical Tablets
Ideal for high-speed tablet production, mini-tablet lines, and large-scale batch manufacture where flow and compressibility are critical.
Capsules
Used as a major filler to ensure consistent dosing and smooth capsule handling.
Granulation Processes
Supports dry granulation (roller compaction) and wet granulation methods.
Nutraceutical Products
Applied in supplement tablets and capsules where content uniformity, flowability, and production scale matter.
Other Solid Formulations
Useful in powders, functional health blends, and other solid dosage formats requiring stable MCC performance.
GMP-Certified Production
Manufactured under strict quality systems to ensure purity, safety, and compliance.
Superior Batch Consistency
High-quality raw materials and rigorous quality control guarantee uniform performance from batch to batch.
Technical Formulation Support
Our experienced team helps you optimize MCC 301 use for flow, compression, and dosage performance.
Custom Grade Options
We offer customization in terms of particle size, bulk density, and moisture content to suit your unique needs.
Reliable Global Supply
Scalable production and global logistics ensure consistent supply to your manufacturing operations.
Q1 – Is MCC 301 ideal for direct compression?
Yes, its coarse particle size and deformable structure make MCC 301 very well-suited for direct compression.
Q2 – Can MCC 301 help solve flow problems in high-speed manufacturing?
Absolutely. The larger particles reduce friction, bridging, and improve overall powder flow.
Q3 – Will tablets made with MCC 301 disintegrate well?
Yes, MCC 301’s porosity and water uptake promote reliable disintegration and release behavior.
Q4 – Is MCC 301 compatible with sensitive APIs?
Yes, it is chemically inert, stable, and non-reactive with a wide range of active pharmaceutical ingredients.
Q5 – What storage conditions does MCC 301 require?
Store in a cool, dry place, protected from moisture and strong humidity to preserve flow and compression performance.
Looking for a high-performance, high-flow MCC 301 to optimize your tablet or capsule production? Partner with Besty Pharma for premium excipients, tailored technical support, and dependable global supply.
