Microcrystalline Cellulose (MCC) 101 is one of the most widely used excipients in pharmaceutical and nutraceutical solid dosage forms. Known for its fine particle size, excellent compressibility, and stable binding performance, MCC 101 ensures superior tablet hardness, uniformity, and stability during high-speed production.
As a trusted excipient manufacturer, Besty Pharma supplies GMP-grade MCC 101 engineered for direct compression, wet granulation, and capsule filling, delivering consistent quality across global pharmaceutical and supplement markets.
MCC 101 is a purified, partially depolymerized cellulose derived from plant fiber. It offers a fine particle size distribution, making it especially effective for direct compression formulations, low-dose actives, and tablets requiring high binding strength.
Its multifunctional properties allow it to act as a:
Binder
Filler
Flow enhancer
Disintegrant power-supporter
Texture stabilizer
MCC 101 remains the industry benchmark for manufacturers seeking stability, performance, and uniformity in solid dosage production.
Produces strong, rigid tablets even at low compression forces
Ensures low friability and high mechanical stability
Ideal for small, fragile, or chewable tablets
Fine particle size enhances interparticle bonding
Supports uniform distribution of active ingredients
Ensures stable hardness during storage and transport
Suitable for high-speed tableting machines
Helps improve powder uniformity and reduces weight variation
Supports smooth capsule filling
Maintains predictable disintegration times
Supports optimal API release and bioavailability
Derived from natural plant cellulose
Non-reactive, chemically stable, and non-toxic
Suitable for pharmaceuticals, nutraceuticals, and food applications
| Parameter | Specification |
|---|---|
| Grade | MCC 101 |
| Appearance | White to off-white powder |
| Assay | Carbohydrate content: (calculated as dried product), 97.0% to 102.0% based on cellulose |
| Particle Size | Fine, small particle distribution |
| Bulk Density | 0.26–0.31 g/ml (typical) |
| Water-soluble substance | ≤ 0.24% |
| pH (10% slurry) | 5.0–7.5 |
| Loss on Drying | ≤ 7.0% |
| Solubility | Insoluble in water; dispersible |
| Functions | Binder, filler, flow aid for tablets & capsules |
| Packaging | 20kg/25kg bags |
| Shelf Life | 24 months under proper storage |
Direct compression formulations
Low-dose and multi-layer tablets
Chewable tablets requiring smooth mouthfeel
Tablets needing strong hardness with low excipient load
Works as a filler to ensure consistent weight and stability
Enhances blend uniformity and flowability
Used in vitamin tablets, herbal tablets, sports nutrition tablets
Supports stable compression for large format tablets
Texture modifier in food products
Stabilizer in personal care formulations
Functional additive in industrial applications
Our production plant is a modern facility with:
Cleanroom processing environments
State-of-the-art milling and drying technology
Fully automated lines that reduce contamination risk
From raw material to final packaging, we maintain strict hygiene protocols. Every team member undergoes regular training. Our workers are not just operators — they’re quality guardians.
You won’t find shortcuts here. We only produce what we’d be proud to use ourselves.
Produced in modern GMP standard workshops to ensure safety, purity, and consistency.
Each batch undergoes rigorous testing for:
Particle size
Compressibility
Microbiological limits
Bulk density
Moisture
In addition to MCC 101, we supply:
MCC 102 – Better flowability for high-speed production
MCC 200 – Larger particle size for specialized tablet lines
MCC 301 – Ultra-fine grade for precision formulations
U receive guidance on:
Selecting the right MCC grade
Formulation optimization
Direct compression troubleshooting
Flow improvement and hardness stability
Competitive pricing, fast delivery, and stable production capacity help U maintain your supply chain with confidence.
1. What is the main difference between MCC 101 and MCC 102?
MCC 101 has a smaller particle size and stronger binding ability, while MCC 102 offers better flowability.
2. Is MCC 101 suitable for direct compression?
Yes. MCC 101 is one of the most commonly used direct compression binders.
3. Can MCC 101 be used in capsules?
Yes. It works as an excellent filler for improving blend uniformity and capsule weight control.
4. Does MCC 101 affect API stability?
No. MCC is chemically inert and does not react with most active ingredients.
5. Can I request customized particle size or moisture levels?
Yes. Besty Pharma provides customized excipient parameters according to your formulation needs.
6. Is MCC 101 safe for food applications?
Yes. MCC is approved for use in food, nutraceutical, and pharmaceutical products.
Choose a trusted partner for high-quality MCC 101.
Besty Pharma supports your formulation success with superior excipients, technical expertise, and reliable global supply.
